Number of Players
1 (Single Player)
Release Date

Game Boy

  • JP 27th Jul 1990
  • EU 30th Apr 1991
  • US 1st Dec 1990

3DS (3DS eShop)

  • JP 27th Jul 2011, ¥400
  • EU 22nd Mar 2012, £2.70
  • US 4th Oct 2012, $3.99

Nintendo Switch Online (Subscription)

  • 12th Mar 2024
Also Available On


  • Review Dr. Mario (3DS eShop / GB)

    The doctor’s out

    If there’s one thing the 3DS eShop has plenty of, it’s puzzle games. It’s a genre that's always been commonplace on Nintendo handhelds, with Tetris probably the best known example. It’s hardly surprising that Nintendo’s mascot extraordinaire, Mario, invaded Game Boy with his own puzzle title, Dr. Mario. Does it make us...

Screenshots 4

Dr. Mario Screenshot
Dr. Mario Screenshot
Dr. Mario Screenshot
Dr. Mario Screenshot

Dr. Mario News

About The Game

Dr. Mario - the prescription is fun.

It's Dr. Mario for an intense new challenge! Mario throws multi-shaded vitamin capsules into a bottle that contains an ugly variety of nasty viruses. You can move, shift or spin the capsules as they fall.

Arrange them to align with other capsules on top of a virus. If you can get 4 or more of the same shade in a row, POOF! They disappear! Destroy all of the viruses in the bottle and you progress to the next round where things get even more difficult.

Dr. Mario, with germs that are fun to catch.