- Q.U.B.E. 2 (Switch eShop)
- Q.U.B.E: Director's Cut (Wii U eShop)
- Qbics Paint (Switch eShop)
- Qbik (Switch eShop)
- QIX (GB)
- Quad Fighter K (Switch eShop)
- Quadcopter Pilot Challenge (Wii U eShop)
- Quake II (N64)
- Quantum of Solace: The Game (Wii)
- Quarantine Circular (Switch eShop)
- Quarth (GB)
- Queen's Garden (Wii U eShop)
- Quell Memento (3DS eShop)
- Quell Reflect (3DS eShop)
- Quest for the Golden Duck (Switch eShop)
- Quest of Dungeons (Wii U eShop)
- Quest of Dungeons (3DS eShop)
- Quest of Dungeons (Switch eShop)
- Quick Fill Q (DSiWare)
- QuickPick Farmer (DSiWare)
- Quiet, Please! (3DS eShop)
- Quiz Party (Wii)