- Q*Bert (GB)
- Q-YO Blaster (Switch eShop)
- Q.U.B.E. 2 (Switch eShop)
- Q.U.B.E: Director's Cut (Wii U eShop)
- Qbics Paint (Switch eShop)
- Qbik (Switch eShop)
- QBillion (GB)
- QIX (GB)
- Quad Fighter K (Switch eShop)
- Quadcopter Pilot Challenge (Wii U eShop)
- Quadle (Switch eShop)
- Quake II (N64)
- Quantum of Solace: The Game (Wii)
- Quarantine Circular (Switch eShop)
- Quarth (GB)
- Queen's Garden (Wii U eShop)
- Queen's Quest 2: Stories of Forgotten Past (Switch eShop)
- Queen's Quest 3: The End of Dawn (Switch eShop)
- Quell Memento (3DS eShop)
- Quell Reflect (3DS eShop)
- Quench (Switch eShop)
- Quest for the Golden Duck (Switch eShop)
- Quest Hunter (Switch eShop)
- Quest of Dungeons (3DS eShop)
- Quest of Dungeons (Switch eShop)
- Quest of Dungeons (Wii U eShop)
- Quick Fill Q (DSiWare)
- Quick Yoga Training (DS)
- QuickPick Farmer (DSiWare)
- QuickSpot (DS)
- Quiet, Please! (3DS eShop)
- Quiz Magic Academy DS (DS)
- Quiz Magic Academy DS: Futatsu no Jik?seki (DS)
- Quiz Party (Wii)
- Qupu!! Mame Goma! (DS)