Well I would say games, but then you'd be competing with DSicade.com which already has a good set up.
But neither DSicade.com or DSsdk.com have decent social sections, so there's a gap.
There's also DScomics.com. These are the 3 main sites I'm aware of that are made just for the DS browser.
Adding a facebook like site for just the DSi would be neat (and good on your resume. ;D) and possibly twitter like funtions maybe? lol
I have no idea how complicated site construction is so whatever you do I'm sure it'll be good. 
Course I wouldn't mind a simple graphical RPG. lol it could tie into the social aspect of the site..bah too complex. 
Also there is a site
http://www.dsibrew.org/wiki/Nintendo_DSi_Browser
That lists some tips and code or whatever to help make the site work better for the DSi if you weren't aware of it already.


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